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Matrix Expansion and Syncytial Aggregation of Syndecan-1(+) Cells Underpin Villous Atrophy in Coeliac Disease

BACKGROUND: We studied the expression of sulphated glycosaminoglycans (GAGs) in coeliac disease (CD) mucosa, as they are critical determinants of tissue volume, which increases in active disease. We also examined mucosal expression of IL-6, which stimulates excess GAG synthesis in disorders such as...

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Detalles Bibliográficos
Autores principales: Salvestrini, Camilla, Lucas, Mark, Lionetti, Paolo, Torrente, Franco, James, Sean, Phillips, Alan D., Murch, Simon H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157760/
https://www.ncbi.nlm.nih.gov/pubmed/25198673
http://dx.doi.org/10.1371/journal.pone.0106005