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Matrix Expansion and Syncytial Aggregation of Syndecan-1(+) Cells Underpin Villous Atrophy in Coeliac Disease
BACKGROUND: We studied the expression of sulphated glycosaminoglycans (GAGs) in coeliac disease (CD) mucosa, as they are critical determinants of tissue volume, which increases in active disease. We also examined mucosal expression of IL-6, which stimulates excess GAG synthesis in disorders such as...
Autores principales: | Salvestrini, Camilla, Lucas, Mark, Lionetti, Paolo, Torrente, Franco, James, Sean, Phillips, Alan D., Murch, Simon H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157760/ https://www.ncbi.nlm.nih.gov/pubmed/25198673 http://dx.doi.org/10.1371/journal.pone.0106005 |
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