Poly(Ethylene Glycol)-Cholesterol Inhibits L-Type Ca(2+) Channel Currents and Augments Voltage-Dependent Inactivation in A7r5 Cells

Cholesterol distributes at a high density in the membrane lipid raft and modulates ion channel currents. Poly(ethylene glycol) cholesteryl ether (PEG-cholesterol) is a nonionic amphipathic lipid consisting of lipophilic cholesterol and covalently bound hydrophilic PEG. PEG-cholesterol is used to for...

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Detalles Bibliográficos
Autores principales: Ochi, Rikuo, Chettimada, Sukrutha, Gupte, Sachin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157810/
https://www.ncbi.nlm.nih.gov/pubmed/25197984
http://dx.doi.org/10.1371/journal.pone.0107049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157810/
https://www.ncbi.nlm.nih.gov/pubmed/25197984
http://dx.doi.org/10.1371/journal.pone.0107049

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