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Inhibition of H3K9 Methyltransferase G9a Repressed Cell Proliferation and Induced Autophagy in Neuroblastoma Cells

Histone methylation plays an important role in gene transcription and chromatin organization and is linked to the silencing of a number of critical tumor suppressor genes in tumorigenesis. G9a is a histone methyltransferase (HMTase) for histone H3 lysine 9. In this study, we investigated the role of...

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Detalles Bibliográficos
Autores principales: Ke, Xiao-Xue, Zhang, Dunke, Zhu, Shunqin, Xia, Qingyou, Xiang, Zhonghuai, Cui, Hongjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157855/
https://www.ncbi.nlm.nih.gov/pubmed/25198515
http://dx.doi.org/10.1371/journal.pone.0106962