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Structural Insights into the Recognition of Phosphopeptide by the FHA Domain of Kanadaptin

Kanadaptin is a nuclear protein of unknown function that is widely expressed in mammalian tissues. The crystal structure of the forkhead-associated (FHA) domain of human kanadaptin was determined to 1.6 Å resolution. The structure reveals an asymmetric dimer in which one monomer is complexed with a...

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Detalles Bibliográficos
Autores principales: Xu, Qingping, Deller, Marc C., Nielsen, Tine K., Grant, Joanna C., Lesley, Scott A., Elsliger, Marc-André, Deacon, Ashley M., Wilson, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157861/
https://www.ncbi.nlm.nih.gov/pubmed/25197798
http://dx.doi.org/10.1371/journal.pone.0107309