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Using Galaxy-P to leverage RNA-Seq for the discovery of novel protein variations

BACKGROUND: Current practice in mass spectrometry (MS)-based proteomics is to identify peptides by comparison of experimental mass spectra with theoretical mass spectra derived from a reference protein database; however, this strategy necessarily fails to detect peptide and protein sequences that ar...

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Detalles Bibliográficos
Autores principales: Sheynkman, Gloria M, Johnson, James E, Jagtap, Pratik D, Shortreed, Michael R, Onsongo, Getiria, Frey, Brian L, Griffin, Timothy J, Smith, Lloyd M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158061/
https://www.ncbi.nlm.nih.gov/pubmed/25149441
http://dx.doi.org/10.1186/1471-2164-15-703