Unexpected detection of Plasmodium vivax and Plasmodium falciparum DNA in asymptomatic blood donors: fact or artifact?

A study searching for Plasmodium vivax and Plasmodium falciparum DNA among blood donors from the non-endemic area in Brazil reported a rate of 7.41%. This number is at least three times higher than what has been observed in blood donors from the Amazon, an endemic area concentrating >99% of all m...

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Autores principales: Mendrone, Alfredo, Cerutti, Crispim, Levi, José Eduardo, Boulos, Marcos, Sanchez, Maria Carmen Arroyo, Malafronte, Rosely dos Santos, Di Santi, Silvia Maria, Odone, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158092/
https://www.ncbi.nlm.nih.gov/pubmed/25168246
http://dx.doi.org/10.1186/1475-2875-13-336
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author Mendrone, Alfredo
Cerutti, Crispim
Levi, José Eduardo
Boulos, Marcos
Sanchez, Maria Carmen Arroyo
Malafronte, Rosely dos Santos
Di Santi, Silvia Maria
Odone, Vicente
author_facet Mendrone, Alfredo
Cerutti, Crispim
Levi, José Eduardo
Boulos, Marcos
Sanchez, Maria Carmen Arroyo
Malafronte, Rosely dos Santos
Di Santi, Silvia Maria
Odone, Vicente
author_sort Mendrone, Alfredo
collection PubMed
description A study searching for Plasmodium vivax and Plasmodium falciparum DNA among blood donors from the non-endemic area in Brazil reported a rate of 7.41%. This number is at least three times higher than what has been observed in blood donors from the Amazon, an endemic area concentrating >99% of all malaria cases in Brazil. Moreover, the majority of the donors were supposedly infected by P. falciparum, a rare finding both in men and anophelines from the Atlantic forest. These findings shall be taken with caution since they disagree with several publications in the literature and possibly overestimate the actual risk of malaria transmission by blood transfusion in São Paulo city.
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spelling pubmed-41580922014-09-10 Unexpected detection of Plasmodium vivax and Plasmodium falciparum DNA in asymptomatic blood donors: fact or artifact? Mendrone, Alfredo Cerutti, Crispim Levi, José Eduardo Boulos, Marcos Sanchez, Maria Carmen Arroyo Malafronte, Rosely dos Santos Di Santi, Silvia Maria Odone, Vicente Malar J Commentary A study searching for Plasmodium vivax and Plasmodium falciparum DNA among blood donors from the non-endemic area in Brazil reported a rate of 7.41%. This number is at least three times higher than what has been observed in blood donors from the Amazon, an endemic area concentrating >99% of all malaria cases in Brazil. Moreover, the majority of the donors were supposedly infected by P. falciparum, a rare finding both in men and anophelines from the Atlantic forest. These findings shall be taken with caution since they disagree with several publications in the literature and possibly overestimate the actual risk of malaria transmission by blood transfusion in São Paulo city. BioMed Central 2014-08-28 /pmc/articles/PMC4158092/ /pubmed/25168246 http://dx.doi.org/10.1186/1475-2875-13-336 Text en © Mendrone et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Commentary
Mendrone, Alfredo
Cerutti, Crispim
Levi, José Eduardo
Boulos, Marcos
Sanchez, Maria Carmen Arroyo
Malafronte, Rosely dos Santos
Di Santi, Silvia Maria
Odone, Vicente
Unexpected detection of Plasmodium vivax and Plasmodium falciparum DNA in asymptomatic blood donors: fact or artifact?
title Unexpected detection of Plasmodium vivax and Plasmodium falciparum DNA in asymptomatic blood donors: fact or artifact?
title_full Unexpected detection of Plasmodium vivax and Plasmodium falciparum DNA in asymptomatic blood donors: fact or artifact?
title_fullStr Unexpected detection of Plasmodium vivax and Plasmodium falciparum DNA in asymptomatic blood donors: fact or artifact?
title_full_unstemmed Unexpected detection of Plasmodium vivax and Plasmodium falciparum DNA in asymptomatic blood donors: fact or artifact?
title_short Unexpected detection of Plasmodium vivax and Plasmodium falciparum DNA in asymptomatic blood donors: fact or artifact?
title_sort unexpected detection of plasmodium vivax and plasmodium falciparum dna in asymptomatic blood donors: fact or artifact?
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158092/
https://www.ncbi.nlm.nih.gov/pubmed/25168246
http://dx.doi.org/10.1186/1475-2875-13-336
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