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4-(2-Fluorophenyl)-2-methoxy-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine-3-carbonitrile
In the title compound, C(19)H(19)FN(2)O, the cyclooctene ring adopts a twisted boat–chair conformation. The dihedral angle between the plane of the fluorophenyl substituent and that of the pyridine ring is 76.39 (8)°. The F and ortho-H atoms of the fluorobenzene ring are disordered, with occupancy...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158480/ https://www.ncbi.nlm.nih.gov/pubmed/25249918 http://dx.doi.org/10.1107/S1600536814016365 |
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| author | Vishnupriya, R. Suresh, J. Maharani, S. Kumar, R. Ranjith Lakshman, P. L. Nilantha |
| author_facet | Vishnupriya, R. Suresh, J. Maharani, S. Kumar, R. Ranjith Lakshman, P. L. Nilantha |
| author_sort | Vishnupriya, R. |
| collection | PubMed |
| description | In the title compound, C(19)H(19)FN(2)O, the cyclooctene ring adopts a twisted boat–chair conformation. The dihedral angle between the plane of the fluorophenyl substituent and that of the pyridine ring is 76.39 (8)°. The F and ortho-H atoms of the fluorobenzene ring are disordered, with occupancy factors of 0.226 (5) and 0.774 (5). In the crystal, no significant interactions are observed between the molecules beyond van der Waals contacts. |
| format | Online Article Text |
| id | pubmed-4158480 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| publisher | International Union of Crystallography |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-41584802014-09-23 4-(2-Fluorophenyl)-2-methoxy-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine-3-carbonitrile Vishnupriya, R. Suresh, J. Maharani, S. Kumar, R. Ranjith Lakshman, P. L. Nilantha Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(19)H(19)FN(2)O, the cyclooctene ring adopts a twisted boat–chair conformation. The dihedral angle between the plane of the fluorophenyl substituent and that of the pyridine ring is 76.39 (8)°. The F and ortho-H atoms of the fluorobenzene ring are disordered, with occupancy factors of 0.226 (5) and 0.774 (5). In the crystal, no significant interactions are observed between the molecules beyond van der Waals contacts. International Union of Crystallography 2014-07-23 /pmc/articles/PMC4158480/ /pubmed/25249918 http://dx.doi.org/10.1107/S1600536814016365 Text en © Vishnupriya et al. 2014 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
| spellingShingle | Organic Papers Vishnupriya, R. Suresh, J. Maharani, S. Kumar, R. Ranjith Lakshman, P. L. Nilantha 4-(2-Fluorophenyl)-2-methoxy-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine-3-carbonitrile |
| title | 4-(2-Fluorophenyl)-2-methoxy-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine-3-carbonitrile |
| title_full | 4-(2-Fluorophenyl)-2-methoxy-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine-3-carbonitrile |
| title_fullStr | 4-(2-Fluorophenyl)-2-methoxy-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine-3-carbonitrile |
| title_full_unstemmed | 4-(2-Fluorophenyl)-2-methoxy-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine-3-carbonitrile |
| title_short | 4-(2-Fluorophenyl)-2-methoxy-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine-3-carbonitrile |
| title_sort | 4-(2-fluorophenyl)-2-methoxy-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine-3-carbonitrile |
| topic | Organic Papers |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158480/ https://www.ncbi.nlm.nih.gov/pubmed/25249918 http://dx.doi.org/10.1107/S1600536814016365 |
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