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Betulin 3,28-di-O-tosyl­ate

The title compound, C(44)H(62)O(6)S(2) {systematic name: (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-5a,5b,8,8,11a-penta­methyl-1-(prop-1-en-2-yl)-3a-[(tos­yloxy)meth­yl]icosa­hydro-1H-cyclo­penta­[a]chrysen-9-yl 4-methyl­benzene­sulfonate}, was obtained by tosyl­ation of naturally occurring betulin...

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Detalles Bibliográficos
Autores principales: Peipiņš, Uldis, Freimanis, Niks, Stepanovs, Dmitrijs, Mishnev, Anatoly, Turks, Māris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158509/
https://www.ncbi.nlm.nih.gov/pubmed/25249923
http://dx.doi.org/10.1107/S1600536814016602
Descripción
Sumario:The title compound, C(44)H(62)O(6)S(2) {systematic name: (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-5a,5b,8,8,11a-penta­methyl-1-(prop-1-en-2-yl)-3a-[(tos­yloxy)meth­yl]icosa­hydro-1H-cyclo­penta­[a]chrysen-9-yl 4-methyl­benzene­sulfonate}, was obtained by tosyl­ation of naturally occurring betulin. All the cyclo­hexane rings adopt chair conformations and the cyclo­pentane ring adopts a twisted envelope conformation, with the C atom bearing the tosyl­methyl substituent forming the flap. In the crystal, mol­ecules form a three-dimensional network through multiple weak C—H⋯O hydrogen bonds.