(5R*)-5-[(2S*,5S*)-1-Meth­oxy-5-phenyl­pyrrolidin-2-yl]-3-methyl­furan-2(5H)-one

In the title compound, C(16)H(19)NO(3), the pyrrolidine ring is in a twist conformation. The dihedral angle between the di­hydro­furan ring [maximum deviation = 0.0016 (11) Å] and the phenyl ring is 47.22 (8)°. In the crystal, mol­ecules are linked by weak C—H⋯O hydrogen bonds, forming helical chain...

Descripción completa

Detalles Bibliográficos
Autores principales: Oishi, Takeshi, Yoritate, Makoto, Sato, Takaaki, Chida, Noritaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158531/
https://www.ncbi.nlm.nih.gov/pubmed/25249892
http://dx.doi.org/10.1107/S1600536814014974
_version_ 1782334068311982080
author Oishi, Takeshi
Yoritate, Makoto
Sato, Takaaki
Chida, Noritaka
author_facet Oishi, Takeshi
Yoritate, Makoto
Sato, Takaaki
Chida, Noritaka
author_sort Oishi, Takeshi
collection PubMed
description In the title compound, C(16)H(19)NO(3), the pyrrolidine ring is in a twist conformation. The dihedral angle between the di­hydro­furan ring [maximum deviation = 0.0016 (11) Å] and the phenyl ring is 47.22 (8)°. In the crystal, mol­ecules are linked by weak C—H⋯O hydrogen bonds, forming helical chains along the b-axis direction. The chains are further linked by C—H⋯π inter­actions to constitute a three-dimensional architecture.
format Online
Article
Text
id pubmed-4158531
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-41585312014-09-23 (5R*)-5-[(2S*,5S*)-1-Meth­oxy-5-phenyl­pyrrolidin-2-yl]-3-methyl­furan-2(5H)-one Oishi, Takeshi Yoritate, Makoto Sato, Takaaki Chida, Noritaka Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(16)H(19)NO(3), the pyrrolidine ring is in a twist conformation. The dihedral angle between the di­hydro­furan ring [maximum deviation = 0.0016 (11) Å] and the phenyl ring is 47.22 (8)°. In the crystal, mol­ecules are linked by weak C—H⋯O hydrogen bonds, forming helical chains along the b-axis direction. The chains are further linked by C—H⋯π inter­actions to constitute a three-dimensional architecture. International Union of Crystallography 2014-07-02 /pmc/articles/PMC4158531/ /pubmed/25249892 http://dx.doi.org/10.1107/S1600536814014974 Text en © Oishi et al. 2014 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Oishi, Takeshi
Yoritate, Makoto
Sato, Takaaki
Chida, Noritaka
(5R*)-5-[(2S*,5S*)-1-Meth­oxy-5-phenyl­pyrrolidin-2-yl]-3-methyl­furan-2(5H)-one
title (5R*)-5-[(2S*,5S*)-1-Meth­oxy-5-phenyl­pyrrolidin-2-yl]-3-methyl­furan-2(5H)-one
title_full (5R*)-5-[(2S*,5S*)-1-Meth­oxy-5-phenyl­pyrrolidin-2-yl]-3-methyl­furan-2(5H)-one
title_fullStr (5R*)-5-[(2S*,5S*)-1-Meth­oxy-5-phenyl­pyrrolidin-2-yl]-3-methyl­furan-2(5H)-one
title_full_unstemmed (5R*)-5-[(2S*,5S*)-1-Meth­oxy-5-phenyl­pyrrolidin-2-yl]-3-methyl­furan-2(5H)-one
title_short (5R*)-5-[(2S*,5S*)-1-Meth­oxy-5-phenyl­pyrrolidin-2-yl]-3-methyl­furan-2(5H)-one
title_sort (5r*)-5-[(2s*,5s*)-1-meth­oxy-5-phenyl­pyrrolidin-2-yl]-3-methyl­furan-2(5h)-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158531/
https://www.ncbi.nlm.nih.gov/pubmed/25249892
http://dx.doi.org/10.1107/S1600536814014974
work_keys_str_mv AT oishitakeshi 5r52s5s1methoxy5phenylpyrrolidin2yl3methylfuran25hone
AT yoritatemakoto 5r52s5s1methoxy5phenylpyrrolidin2yl3methylfuran25hone
AT satotakaaki 5r52s5s1methoxy5phenylpyrrolidin2yl3methylfuran25hone
AT chidanoritaka 5r52s5s1methoxy5phenylpyrrolidin2yl3methylfuran25hone

Ejemplares similares