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Tackling a Recurrent Pinealoblastoma

Pineoblastomas are rare, malignant, pineal region lesions that account for <0.1% of all intracranial tumors and can metastasize along the neuroaxis. Pineoblastomas are more common in children than in adults and adults account for <10% of patients. The management of pinealoblastoma is multimoda...

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Detalles Bibliográficos
Autores principales: Palled, Siddanna, Kalavagunta, Sruthi, Beerappa Gowda, Jaipal, Umesh, Kavita, Aal, Mahalaxmi, Abdul Razack, Tanvir pasha Chitraduraga, Gowda, Veerabhadre, Viswanath, Lokesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158562/
https://www.ncbi.nlm.nih.gov/pubmed/25210636
http://dx.doi.org/10.1155/2014/135435
Descripción
Sumario:Pineoblastomas are rare, malignant, pineal region lesions that account for <0.1% of all intracranial tumors and can metastasize along the neuroaxis. Pineoblastomas are more common in children than in adults and adults account for <10% of patients. The management of pinealoblastoma is multimodality approach, surgery followed with radiation and chemotherapy. In view of aggressive nature few centres use high dose chemotherapy with autologus stem cell transplant in newly diagnosed cases but in recurrent setting the literature is very sparse. The present case represents the management of pinealoblastoma in the recurrent setting with reirradiation and adjuvant carmustine chemotherapy wherein the management guidelines are not definitive.