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Tackling a Recurrent Pinealoblastoma

Pineoblastomas are rare, malignant, pineal region lesions that account for <0.1% of all intracranial tumors and can metastasize along the neuroaxis. Pineoblastomas are more common in children than in adults and adults account for <10% of patients. The management of pinealoblastoma is multimoda...

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Autores principales: Palled, Siddanna, Kalavagunta, Sruthi, Beerappa Gowda, Jaipal, Umesh, Kavita, Aal, Mahalaxmi, Abdul Razack, Tanvir pasha Chitraduraga, Gowda, Veerabhadre, Viswanath, Lokesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158562/
https://www.ncbi.nlm.nih.gov/pubmed/25210636
http://dx.doi.org/10.1155/2014/135435
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author Palled, Siddanna
Kalavagunta, Sruthi
Beerappa Gowda, Jaipal
Umesh, Kavita
Aal, Mahalaxmi
Abdul Razack, Tanvir pasha Chitraduraga
Gowda, Veerabhadre
Viswanath, Lokesh
author_facet Palled, Siddanna
Kalavagunta, Sruthi
Beerappa Gowda, Jaipal
Umesh, Kavita
Aal, Mahalaxmi
Abdul Razack, Tanvir pasha Chitraduraga
Gowda, Veerabhadre
Viswanath, Lokesh
author_sort Palled, Siddanna
collection PubMed
description Pineoblastomas are rare, malignant, pineal region lesions that account for <0.1% of all intracranial tumors and can metastasize along the neuroaxis. Pineoblastomas are more common in children than in adults and adults account for <10% of patients. The management of pinealoblastoma is multimodality approach, surgery followed with radiation and chemotherapy. In view of aggressive nature few centres use high dose chemotherapy with autologus stem cell transplant in newly diagnosed cases but in recurrent setting the literature is very sparse. The present case represents the management of pinealoblastoma in the recurrent setting with reirradiation and adjuvant carmustine chemotherapy wherein the management guidelines are not definitive.
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spelling pubmed-41585622014-09-10 Tackling a Recurrent Pinealoblastoma Palled, Siddanna Kalavagunta, Sruthi Beerappa Gowda, Jaipal Umesh, Kavita Aal, Mahalaxmi Abdul Razack, Tanvir pasha Chitraduraga Gowda, Veerabhadre Viswanath, Lokesh Case Rep Oncol Med Case Report Pineoblastomas are rare, malignant, pineal region lesions that account for <0.1% of all intracranial tumors and can metastasize along the neuroaxis. Pineoblastomas are more common in children than in adults and adults account for <10% of patients. The management of pinealoblastoma is multimodality approach, surgery followed with radiation and chemotherapy. In view of aggressive nature few centres use high dose chemotherapy with autologus stem cell transplant in newly diagnosed cases but in recurrent setting the literature is very sparse. The present case represents the management of pinealoblastoma in the recurrent setting with reirradiation and adjuvant carmustine chemotherapy wherein the management guidelines are not definitive. Hindawi Publishing Corporation 2014 2014-08-25 /pmc/articles/PMC4158562/ /pubmed/25210636 http://dx.doi.org/10.1155/2014/135435 Text en Copyright © 2014 Siddanna Palled et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Palled, Siddanna
Kalavagunta, Sruthi
Beerappa Gowda, Jaipal
Umesh, Kavita
Aal, Mahalaxmi
Abdul Razack, Tanvir pasha Chitraduraga
Gowda, Veerabhadre
Viswanath, Lokesh
Tackling a Recurrent Pinealoblastoma
title Tackling a Recurrent Pinealoblastoma
title_full Tackling a Recurrent Pinealoblastoma
title_fullStr Tackling a Recurrent Pinealoblastoma
title_full_unstemmed Tackling a Recurrent Pinealoblastoma
title_short Tackling a Recurrent Pinealoblastoma
title_sort tackling a recurrent pinealoblastoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158562/
https://www.ncbi.nlm.nih.gov/pubmed/25210636
http://dx.doi.org/10.1155/2014/135435
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