Cargando…
Tackling a Recurrent Pinealoblastoma
Pineoblastomas are rare, malignant, pineal region lesions that account for <0.1% of all intracranial tumors and can metastasize along the neuroaxis. Pineoblastomas are more common in children than in adults and adults account for <10% of patients. The management of pinealoblastoma is multimoda...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158562/ https://www.ncbi.nlm.nih.gov/pubmed/25210636 http://dx.doi.org/10.1155/2014/135435 |
_version_ | 1782334077173497856 |
---|---|
author | Palled, Siddanna Kalavagunta, Sruthi Beerappa Gowda, Jaipal Umesh, Kavita Aal, Mahalaxmi Abdul Razack, Tanvir pasha Chitraduraga Gowda, Veerabhadre Viswanath, Lokesh |
author_facet | Palled, Siddanna Kalavagunta, Sruthi Beerappa Gowda, Jaipal Umesh, Kavita Aal, Mahalaxmi Abdul Razack, Tanvir pasha Chitraduraga Gowda, Veerabhadre Viswanath, Lokesh |
author_sort | Palled, Siddanna |
collection | PubMed |
description | Pineoblastomas are rare, malignant, pineal region lesions that account for <0.1% of all intracranial tumors and can metastasize along the neuroaxis. Pineoblastomas are more common in children than in adults and adults account for <10% of patients. The management of pinealoblastoma is multimodality approach, surgery followed with radiation and chemotherapy. In view of aggressive nature few centres use high dose chemotherapy with autologus stem cell transplant in newly diagnosed cases but in recurrent setting the literature is very sparse. The present case represents the management of pinealoblastoma in the recurrent setting with reirradiation and adjuvant carmustine chemotherapy wherein the management guidelines are not definitive. |
format | Online Article Text |
id | pubmed-4158562 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-41585622014-09-10 Tackling a Recurrent Pinealoblastoma Palled, Siddanna Kalavagunta, Sruthi Beerappa Gowda, Jaipal Umesh, Kavita Aal, Mahalaxmi Abdul Razack, Tanvir pasha Chitraduraga Gowda, Veerabhadre Viswanath, Lokesh Case Rep Oncol Med Case Report Pineoblastomas are rare, malignant, pineal region lesions that account for <0.1% of all intracranial tumors and can metastasize along the neuroaxis. Pineoblastomas are more common in children than in adults and adults account for <10% of patients. The management of pinealoblastoma is multimodality approach, surgery followed with radiation and chemotherapy. In view of aggressive nature few centres use high dose chemotherapy with autologus stem cell transplant in newly diagnosed cases but in recurrent setting the literature is very sparse. The present case represents the management of pinealoblastoma in the recurrent setting with reirradiation and adjuvant carmustine chemotherapy wherein the management guidelines are not definitive. Hindawi Publishing Corporation 2014 2014-08-25 /pmc/articles/PMC4158562/ /pubmed/25210636 http://dx.doi.org/10.1155/2014/135435 Text en Copyright © 2014 Siddanna Palled et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Palled, Siddanna Kalavagunta, Sruthi Beerappa Gowda, Jaipal Umesh, Kavita Aal, Mahalaxmi Abdul Razack, Tanvir pasha Chitraduraga Gowda, Veerabhadre Viswanath, Lokesh Tackling a Recurrent Pinealoblastoma |
title | Tackling a Recurrent Pinealoblastoma |
title_full | Tackling a Recurrent Pinealoblastoma |
title_fullStr | Tackling a Recurrent Pinealoblastoma |
title_full_unstemmed | Tackling a Recurrent Pinealoblastoma |
title_short | Tackling a Recurrent Pinealoblastoma |
title_sort | tackling a recurrent pinealoblastoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158562/ https://www.ncbi.nlm.nih.gov/pubmed/25210636 http://dx.doi.org/10.1155/2014/135435 |
work_keys_str_mv | AT palledsiddanna tacklingarecurrentpinealoblastoma AT kalavaguntasruthi tacklingarecurrentpinealoblastoma AT beerappagowdajaipal tacklingarecurrentpinealoblastoma AT umeshkavita tacklingarecurrentpinealoblastoma AT aalmahalaxmi tacklingarecurrentpinealoblastoma AT abdulrazacktanvirpashachitraduraga tacklingarecurrentpinealoblastoma AT gowdaveerabhadre tacklingarecurrentpinealoblastoma AT viswanathlokesh tacklingarecurrentpinealoblastoma |