Beyond Goosebumps: Does the Arrector Pili Muscle Have a Role in Hair Loss?

The arrector pili muscle (APM) consists of a small band of smooth muscle that connects the hair follicle to the connective tissue of the basement membrane. The APM mediates thermoregulation by contracting to increase air-trapping, but was thought to be vestigial in humans. The APM attaches proximall...

Descripción completa

Detalles Bibliográficos
Autores principales: Torkamani, Niloufar, Rufaut, Nicholas W, Jones, Leslie, Sinclair, Rodney D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158628/
https://www.ncbi.nlm.nih.gov/pubmed/25210331
http://dx.doi.org/10.4103/0974-7753.139077
_version_ 1782334093176864768
author Torkamani, Niloufar
Rufaut, Nicholas W
Jones, Leslie
Sinclair, Rodney D
author_facet Torkamani, Niloufar
Rufaut, Nicholas W
Jones, Leslie
Sinclair, Rodney D
author_sort Torkamani, Niloufar
collection PubMed
description The arrector pili muscle (APM) consists of a small band of smooth muscle that connects the hair follicle to the connective tissue of the basement membrane. The APM mediates thermoregulation by contracting to increase air-trapping, but was thought to be vestigial in humans. The APM attaches proximally to the hair follicle at the bulge, a known stem cell niche. Recent studies have been directed toward this muscle's possible role in maintaining the follicular integrity and stability. This review summarizes APM anatomy and physiology and then discusses the relationship between the follicular unit and the APM. The potential role of the APM in hair loss disorders is also described, and a model explaining APM changes in hair loss is proposed.
format Online
Article
Text
id pubmed-4158628
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-41586282014-09-10 Beyond Goosebumps: Does the Arrector Pili Muscle Have a Role in Hair Loss? Torkamani, Niloufar Rufaut, Nicholas W Jones, Leslie Sinclair, Rodney D Int J Trichology Review Article The arrector pili muscle (APM) consists of a small band of smooth muscle that connects the hair follicle to the connective tissue of the basement membrane. The APM mediates thermoregulation by contracting to increase air-trapping, but was thought to be vestigial in humans. The APM attaches proximally to the hair follicle at the bulge, a known stem cell niche. Recent studies have been directed toward this muscle's possible role in maintaining the follicular integrity and stability. This review summarizes APM anatomy and physiology and then discusses the relationship between the follicular unit and the APM. The potential role of the APM in hair loss disorders is also described, and a model explaining APM changes in hair loss is proposed. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4158628/ /pubmed/25210331 http://dx.doi.org/10.4103/0974-7753.139077 Text en Copyright: © International Journal of Trichology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Torkamani, Niloufar
Rufaut, Nicholas W
Jones, Leslie
Sinclair, Rodney D
Beyond Goosebumps: Does the Arrector Pili Muscle Have a Role in Hair Loss?
title Beyond Goosebumps: Does the Arrector Pili Muscle Have a Role in Hair Loss?
title_full Beyond Goosebumps: Does the Arrector Pili Muscle Have a Role in Hair Loss?
title_fullStr Beyond Goosebumps: Does the Arrector Pili Muscle Have a Role in Hair Loss?
title_full_unstemmed Beyond Goosebumps: Does the Arrector Pili Muscle Have a Role in Hair Loss?
title_short Beyond Goosebumps: Does the Arrector Pili Muscle Have a Role in Hair Loss?
title_sort beyond goosebumps: does the arrector pili muscle have a role in hair loss?
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158628/
https://www.ncbi.nlm.nih.gov/pubmed/25210331
http://dx.doi.org/10.4103/0974-7753.139077
work_keys_str_mv AT torkamaniniloufar beyondgoosebumpsdoesthearrectorpilimusclehavearoleinhairloss
AT rufautnicholasw beyondgoosebumpsdoesthearrectorpilimusclehavearoleinhairloss
AT jonesleslie beyondgoosebumpsdoesthearrectorpilimusclehavearoleinhairloss
AT sinclairrodneyd beyondgoosebumpsdoesthearrectorpilimusclehavearoleinhairloss

Ejemplares similares