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Crucial role of calbindin-D(28k) in the pathogenesis of Alzheimer's disease mouse model
Calbindin-D(28k) (CB), one of the major calcium-binding and buffering proteins, has a critical role in preventing a neuronal death as well as maintaining calcium homeostasis. Although marked reductions of CB expression have been observed in the brains of mice and humans with Alzheimer disease (AD),...
Autores principales: | Kook, S-Y, Jeong, H, Kang, M J, Park, R, Shin, H J, Han, S-H, Son, S M, Song, H, Baik, S H, Moon, M, Yi, E C, Hwang, D, Mook-Jung, I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158683/ https://www.ncbi.nlm.nih.gov/pubmed/24853300 http://dx.doi.org/10.1038/cdd.2014.67 |
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