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Scanning pattern of diffusion tensor tractography and an analysis of the morphology and function of spinal nerve roots

Radiculopathy, commonly induced by intervertebral disk bulging or protrusion, is presently diagnosed in accordance with clinical symptoms because there is no objective quantitative diagnostic criterion. Diffusion tensor magnetic resonance imaging and diffusion tensor tractography revealed the charac...

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Autores principales: Tian, Xin, Liu, Huaijun, Geng, Zuojun, Yang, Hua, Wang, Guoshi, Yang, Jiping, Wang, Chunxia, Li, Cuining, Li, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158705/
https://www.ncbi.nlm.nih.gov/pubmed/25206637
http://dx.doi.org/10.3969/j.issn.1673-5374.2013.33.010
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author Tian, Xin
Liu, Huaijun
Geng, Zuojun
Yang, Hua
Wang, Guoshi
Yang, Jiping
Wang, Chunxia
Li, Cuining
Li, Ying
author_facet Tian, Xin
Liu, Huaijun
Geng, Zuojun
Yang, Hua
Wang, Guoshi
Yang, Jiping
Wang, Chunxia
Li, Cuining
Li, Ying
author_sort Tian, Xin
collection PubMed
description Radiculopathy, commonly induced by intervertebral disk bulging or protrusion, is presently diagnosed in accordance with clinical symptoms because there is no objective quantitative diagnostic criterion. Diffusion tensor magnetic resonance imaging and diffusion tensor tractography revealed the characterization of anisotropic diffusion and displayed the anatomic form of nerve root fibers. This study included 18 cases with intervertebral disc degeneration-induced unilateral radiculopathy. Magnetic resonance diffusion tensor imaging was creatively used to reveal the scanning pattern of fiber tracking of the spinal nerve root. A scoring system of nerve root morphology was used to quantitatively assess nerve root morphology and functional alteration after intervertebral disc degeneration. Results showed that after fiber tracking, compared with unaffected nerve root, fiber bundles gathered together and interrupted at the affected side. No significant alteration was detected in the number of fiber bundles, but the cross-sectional area of nerve root fibers was reduced. These results suggest that diffusion tensor magnetic resonance imaging-based tractography can be used to quantitatively evaluate nerve root function according to the area and morphology of fiber bundles of nerve roots.
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spelling pubmed-41587052014-09-09 Scanning pattern of diffusion tensor tractography and an analysis of the morphology and function of spinal nerve roots Tian, Xin Liu, Huaijun Geng, Zuojun Yang, Hua Wang, Guoshi Yang, Jiping Wang, Chunxia Li, Cuining Li, Ying Neural Regen Res Research and Report Article: Peripheral Nerve Injury and Neural Regeneration Radiculopathy, commonly induced by intervertebral disk bulging or protrusion, is presently diagnosed in accordance with clinical symptoms because there is no objective quantitative diagnostic criterion. Diffusion tensor magnetic resonance imaging and diffusion tensor tractography revealed the characterization of anisotropic diffusion and displayed the anatomic form of nerve root fibers. This study included 18 cases with intervertebral disc degeneration-induced unilateral radiculopathy. Magnetic resonance diffusion tensor imaging was creatively used to reveal the scanning pattern of fiber tracking of the spinal nerve root. A scoring system of nerve root morphology was used to quantitatively assess nerve root morphology and functional alteration after intervertebral disc degeneration. Results showed that after fiber tracking, compared with unaffected nerve root, fiber bundles gathered together and interrupted at the affected side. No significant alteration was detected in the number of fiber bundles, but the cross-sectional area of nerve root fibers was reduced. These results suggest that diffusion tensor magnetic resonance imaging-based tractography can be used to quantitatively evaluate nerve root function according to the area and morphology of fiber bundles of nerve roots. Medknow Publications & Media Pvt Ltd 2013-11-25 /pmc/articles/PMC4158705/ /pubmed/25206637 http://dx.doi.org/10.3969/j.issn.1673-5374.2013.33.010 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research and Report Article: Peripheral Nerve Injury and Neural Regeneration
Tian, Xin
Liu, Huaijun
Geng, Zuojun
Yang, Hua
Wang, Guoshi
Yang, Jiping
Wang, Chunxia
Li, Cuining
Li, Ying
Scanning pattern of diffusion tensor tractography and an analysis of the morphology and function of spinal nerve roots
title Scanning pattern of diffusion tensor tractography and an analysis of the morphology and function of spinal nerve roots
title_full Scanning pattern of diffusion tensor tractography and an analysis of the morphology and function of spinal nerve roots
title_fullStr Scanning pattern of diffusion tensor tractography and an analysis of the morphology and function of spinal nerve roots
title_full_unstemmed Scanning pattern of diffusion tensor tractography and an analysis of the morphology and function of spinal nerve roots
title_short Scanning pattern of diffusion tensor tractography and an analysis of the morphology and function of spinal nerve roots
title_sort scanning pattern of diffusion tensor tractography and an analysis of the morphology and function of spinal nerve roots
topic Research and Report Article: Peripheral Nerve Injury and Neural Regeneration
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158705/
https://www.ncbi.nlm.nih.gov/pubmed/25206637
http://dx.doi.org/10.3969/j.issn.1673-5374.2013.33.010
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