High resolution mapping of modified DNA nucleobases using excision repair enzymes

The incorporation and creation of modified nucleobases in DNA have profound effects on genome function. We describe methods for mapping positions and local content of modified DNA nucleobases in genomic DNA. We combined in vitro nucleobase excision with massively parallel DNA sequencing (Excision-se...

Descripción completa

Detalles Bibliográficos
Autores principales: Bryan, D. Suzi, Ransom, Monica, Adane, Biniam, York, Kerri, Hesselberth, Jay R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158761/
https://www.ncbi.nlm.nih.gov/pubmed/25015380
http://dx.doi.org/10.1101/gr.174052.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158761/
https://www.ncbi.nlm.nih.gov/pubmed/25015380
http://dx.doi.org/10.1101/gr.174052.114

Ejemplares similares