Synthesis of Some New 3-Coumarinoyl Pyridinium and Quinolinium Bromides for their Antimicrobial Activity

3-Bromo acetyl coumarins (4a-c) on treatment with methyl and ethyl esters of nicotinic acid, isonicotinic acid (5a-d) gave 3-coumrinoyl pyridinium bromides (7a-l) and with quinoline (6) gave 3-coumarinoyl quinolinium bromides (8a-c). The structures of the final compounds were established by their sp...

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Autores principales: Porwal, Brajesh, Jayashree, B.S., Attimarad, Mahesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158894/
https://www.ncbi.nlm.nih.gov/pubmed/25206250
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author Porwal, Brajesh
Jayashree, B.S.
Attimarad, Mahesh
author_facet Porwal, Brajesh
Jayashree, B.S.
Attimarad, Mahesh
author_sort Porwal, Brajesh
collection PubMed
description 3-Bromo acetyl coumarins (4a-c) on treatment with methyl and ethyl esters of nicotinic acid, isonicotinic acid (5a-d) gave 3-coumrinoyl pyridinium bromides (7a-l) and with quinoline (6) gave 3-coumarinoyl quinolinium bromides (8a-c). The structures of the final compounds were established by their spectral data. The antimicrobial activitiy of all the newly synthesized test compounds were evaluated and some of them, showed good antibacterial activity.
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spelling pubmed-41588942014-09-09 Synthesis of Some New 3-Coumarinoyl Pyridinium and Quinolinium Bromides for their Antimicrobial Activity Porwal, Brajesh Jayashree, B.S. Attimarad, Mahesh J Basic Clin Pharm Original Article 3-Bromo acetyl coumarins (4a-c) on treatment with methyl and ethyl esters of nicotinic acid, isonicotinic acid (5a-d) gave 3-coumrinoyl pyridinium bromides (7a-l) and with quinoline (6) gave 3-coumarinoyl quinolinium bromides (8a-c). The structures of the final compounds were established by their spectral data. The antimicrobial activitiy of all the newly synthesized test compounds were evaluated and some of them, showed good antibacterial activity. Medknow Publications & Media Pvt Ltd 2009-12 2010-02-15 /pmc/articles/PMC4158894/ /pubmed/25206250 Text en Copyright: © Journal of Basic and Clinical Pharmacy http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Porwal, Brajesh
Jayashree, B.S.
Attimarad, Mahesh
Synthesis of Some New 3-Coumarinoyl Pyridinium and Quinolinium Bromides for their Antimicrobial Activity
title Synthesis of Some New 3-Coumarinoyl Pyridinium and Quinolinium Bromides for their Antimicrobial Activity
title_full Synthesis of Some New 3-Coumarinoyl Pyridinium and Quinolinium Bromides for their Antimicrobial Activity
title_fullStr Synthesis of Some New 3-Coumarinoyl Pyridinium and Quinolinium Bromides for their Antimicrobial Activity
title_full_unstemmed Synthesis of Some New 3-Coumarinoyl Pyridinium and Quinolinium Bromides for their Antimicrobial Activity
title_short Synthesis of Some New 3-Coumarinoyl Pyridinium and Quinolinium Bromides for their Antimicrobial Activity
title_sort synthesis of some new 3-coumarinoyl pyridinium and quinolinium bromides for their antimicrobial activity
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158894/
https://www.ncbi.nlm.nih.gov/pubmed/25206250
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AT attimaradmahesh synthesisofsomenew3coumarinoylpyridiniumandquinoliniumbromidesfortheirantimicrobialactivity

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