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In vitro reconstitution of a highly processive recombinant human dynein complex

Cytoplasmic dynein is an approximately 1.4 MDa multi-protein complex that transports many cellular cargoes towards the minus ends of microtubules. Several in vitro studies of mammalian dynein have suggested that individual motors are not robustly processive, raising questions about how dynein-associ...

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Detalles Bibliográficos
Autores principales: Schlager, Max A, Hoang, Ha Thi, Urnavicius, Linas, Bullock, Simon L, Carter, Andrew P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158905/
https://www.ncbi.nlm.nih.gov/pubmed/24986880
http://dx.doi.org/10.15252/embj.201488792