IRF8 Is a Critical Transcription Factor for Transforming Microglia into a Reactive Phenotype

Microglia become activated by multiple types of damage in the nervous system and play essential roles in neuronal pathologies. However, how micro-glia transform into reactive phenotypes is poorly understood. Here, we identify the transcription factor interferon regulatory factor 8 (IRF8) as a critic...

Descripción completa

Detalles Bibliográficos
Autores principales: Masuda, Takahiro, Tsuda, Makoto, Yoshinaga, Ryohei, Tozaki-Saitoh, Hidetoshi, Ozato, Keiko, Tamura, Tomohiko, Inoue, Kazuhide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158926/
https://www.ncbi.nlm.nih.gov/pubmed/22832225
http://dx.doi.org/10.1016/j.celrep.2012.02.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158926/
https://www.ncbi.nlm.nih.gov/pubmed/22832225
http://dx.doi.org/10.1016/j.celrep.2012.02.014

Ejemplares similares