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IRF8 Is a Critical Transcription Factor for Transforming Microglia into a Reactive Phenotype

Microglia become activated by multiple types of damage in the nervous system and play essential roles in neuronal pathologies. However, how micro-glia transform into reactive phenotypes is poorly understood. Here, we identify the transcription factor interferon regulatory factor 8 (IRF8) as a critic...

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Detalles Bibliográficos
Autores principales:	Masuda, Takahiro, Tsuda, Makoto, Yoshinaga, Ryohei, Tozaki-Saitoh, Hidetoshi, Ozato, Keiko, Tamura, Tomohiko, Inoue, Kazuhide
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158926/ https://www.ncbi.nlm.nih.gov/pubmed/22832225 http://dx.doi.org/10.1016/j.celrep.2012.02.014

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