Methylation profiling of SOCS1, SOCS2, SOCS3, CISH and SHP1 in Philadelphia-negative myeloproliferative neoplasm

Janus kinase-signal transducer and activator of transcription (JAK/STAT) signalling, pivotal in Philadelphia-negative (Ph-ve) myeloproliferative neoplasm (MPN), is negatively regulated by molecules including SOCSs, CISH and SHP1. SOCS1, SOCS2 and SOCS3 methylation have been studied in MPN with disco...

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Detalles Bibliográficos
Autores principales: Zhang, Min Yue, Fung, Tsz Kin, Chen, Fang Yuan, Chim, Chor Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159021/
https://www.ncbi.nlm.nih.gov/pubmed/24131863
http://dx.doi.org/10.1111/jcmm.12103

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