Dynamic Modelling of Pathways to Cellular Senescence Reveals Strategies for Targeted Interventions

Cellular senescence, a state of irreversible cell cycle arrest, is thought to help protect an organism from cancer, yet also contributes to ageing. The changes which occur in senescence are controlled by networks of multiple signalling and feedback pathways at the cellular level, and the interplay b...

Descripción completa

Detalles Bibliográficos
Autores principales: Dalle Pezze, Piero, Nelson, Glyn, Otten, Elsje G., Korolchuk, Viktor I., Kirkwood, Thomas B. L., von Zglinicki, Thomas, Shanley, Daryl P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159174/
https://www.ncbi.nlm.nih.gov/pubmed/25166345
http://dx.doi.org/10.1371/journal.pcbi.1003728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159174/
https://www.ncbi.nlm.nih.gov/pubmed/25166345
http://dx.doi.org/10.1371/journal.pcbi.1003728

Ejemplares similares