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Dynamic Modelling of Pathways to Cellular Senescence Reveals Strategies for Targeted Interventions
Cellular senescence, a state of irreversible cell cycle arrest, is thought to help protect an organism from cancer, yet also contributes to ageing. The changes which occur in senescence are controlled by networks of multiple signalling and feedback pathways at the cellular level, and the interplay b...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159174/ https://www.ncbi.nlm.nih.gov/pubmed/25166345 http://dx.doi.org/10.1371/journal.pcbi.1003728 |