Cargando…

Accelerating Translational Research by Clinically Driven Development of an Informatics Platform–A Case Study

Translational medicine is becoming increasingly dependent upon data generated from health care, clinical research, and molecular investigations. This increasing rate of production and diversity in data has brought about several challenges, including the need to integrate fragmented databases, enable...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abugessaisa, Imad, Saevarsdottir, Saedis, Tsipras, Giorgos, Lindblad, Staffan, Sandin, Charlotta, Nikamo, Pernilla, Ståhle, Mona, Malmström, Vivianne, Klareskog, Lars, Tegnér, Jesper
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159182/ https://www.ncbi.nlm.nih.gov/pubmed/25203647 http://dx.doi.org/10.1371/journal.pone.0104382

Ejemplares similares

Implementation of the CDC translational informatics platform - from genetic variants to the national Swedish Rheumatology Quality Register
por: Abugessaisa, Imad, et al.
Publicado: (2013)

Genetic Association with ERAP1 in Psoriasis Is Confined to Disease Onset after Puberty and Not Dependent on HLA-C*06
por: Lysell, Josefin, et al.
Publicado: (2013)

Occupational exposure to asbestos and silica and risk of developing rheumatoid arthritis: findings from a Swedish population-based case-control study
por: Ilar, Anna, et al.
Publicado: (2019)

Conditional Disease Development extracted from Longitudinal Health Care Cohort Data using Layered Network Construction
por: Kannan, Venkateshan, et al.
Publicado: (2016)

Remaining Pain in Early Rheumatoid Arthritis Patients Treated With Methotrexate
por: Altawil, Reem, et al.
Publicado: (2016)

Postmenopausal hormone therapy and the risk of rheumatoid arthritis: results from the Swedish EIRA population-based case-control study
por: Orellana, Cecilia, et al.
Publicado: (2015)

Oral contraceptives, breastfeeding and the risk of developing rheumatoid arthritis: results from the Swedish EIRA study
por: Orellana, Cecilia, et al.
Publicado: (2017)

Is tea consumption associated with reduction of risk of rheumatoid arthritis? A Swedish case-control study
por: Westerlind, Helga, et al.
Publicado: (2021)

Higher education is associated with a better rheumatoid arthritis outcome concerning for pain and function but not disease activity: results from the EIRA cohort and Swedish rheumatology register
por: Jiang, Xia, et al.
Publicado: (2015)

Sleep problems in rheumatoid arthritis over 12 years from diagnosis: results from the Swedish EIRA study
por: Lyne, Lauren, et al.
Publicado: (2022)

STATegra EMS: an Experiment Management System for complex next-generation omics experiments
por: Hernández-de-Diego, Rafael, et al.
Publicado: (2014)

Modulating co-stimulation: a rational strategy in the treatment of rheumatoid arthritis?
por: Malmström, Vivianne, et al.
Publicado: (2005)

Association of Cardiovascular and Metabolic Disease Genes with Psoriasis
por: Lu, Yingchang, et al.
Publicado: (2012)

Mannan Binding Lectin (MBL) genotypes coding for high MBL serum levels are associated with rheumatoid factor negative rheumatoid arthritis in never smokers
por: Saevarsdottir, Saedis, et al.
Publicado: (2011)

The prevalence of ADH1B and OPRM1 alleles predisposing for alcohol consumption are increased in the Hungarian psoriasis population
por: Szentkereszty-Kovács, Zita, et al.
Publicado: (2019)

Anticollagen type II antibodies are associated with an acute onset rheumatoid arthritis phenotype and prognosticate lower degree of inflammation during 5 years follow-up
por: Manivel, Vivek Anand, et al.
Publicado: (2017)

Parity influences the severity of ACPA-negative early rheumatoid arthritis: a cohort study based on the Swedish EIRA material
por: Pikwer, Mitra, et al.
Publicado: (2015)

Neither low social support nor low decision latitude at work is associated with disease remission among patients with rheumatoid arthritis: results from the Swedish EIRA study
por: Hedenstierna, Louise, et al.
Publicado: (2022)

Data integration in the era of omics: current and future challenges
por: Gomez-Cabrero, David, et al.
Publicado: (2014)

CD25(bright)CD4(+ )regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease
por: Cao, Duojia, et al.
Publicado: (2004)

Risk of Thyroxine-Treated Autoimmune Thyroid Disease Associated With Disease Onset in Patients With Rheumatoid Arthritis
por: Waldenlind, Kristin, et al.
Publicado: (2018)

Does autoimmune thyroid disease affects rheumatoid arthritis disease activity or response to methotrexate?
por: Waldenlind, Kristin, et al.
Publicado: (2020)

The cancer translational research informatics platform
por: McConnell, Patrick, et al.
Publicado: (2008)

Haplotype-Specific Expression Analysis of MHC Class II Genes in Healthy Individuals and Rheumatoid Arthritis Patients
por: Houtman, Miranda, et al.
Publicado: (2021)

Genome informatics for data-driven biology
por: Nakai, Kenta, et al.
Publicado: (2002)

tranSMART: An Open Source and Community-Driven Informatics and Data Sharing Platform for Clinical and Translational Research
por: Athey, Brian D., et al.
Publicado: (2013)

Changes in the anticitrullinated peptide antibody response in relation to therapeutic outcome in early rheumatoid arthritis: results from the SWEFOT trial
por: Kastbom, Alf, et al.
Publicado: (2016)

Comorbidities and treatment patterns in early rheumatoid arthritis: a nationwide Swedish study
por: Tidblad, Liselotte, et al.
Publicado: (2022)

Combined Conventional Synthetic Disease Modifying Therapy vs. Infliximab for Rheumatoid Arthritis: Emulating a Randomized Trial in Observational Data
por: Barbulescu, Andrei, et al.
Publicado: (2022)

An integrated informatics platform to facilitate transforming tissue into knowledge
por: Quinlan, PR, et al.
Publicado: (2010)

Is Android or iPhone the Platform for Innovation in Imaging Informatics
por: Shih, George, et al.
Publicado: (2009)

HAFNI-enabled largescale platform for neuroimaging informatics (HELPNI)
por: Makkie, Milad, et al.
Publicado: (2015)

A mouse informatics platform for phenotypic and translational discovery
por: Ring, Natalie, et al.
Publicado: (2015)

An introduction to healthcare informatics: building data-driven tools
por: Mccaffrey, Peter
Publicado: (2020)

Informatics driven quality improvement in the modern histology lab
por: Seifert, Robert P, et al.
Publicado: (2020)

Evaluating recommender systems for AI-driven biomedical informatics
por: La Cava, William, et al.
Publicado: (2020)

Healthcare Informatics Research's Journey of Paving the Road to Excellence in Global Healthcare Informatics
por: Choi, Mona, et al.
Publicado: (2018)

Non-HLA genes PTPN22, CDK6 and PADI4 are associated with specific autoantibodies in HLA-defined subgroups of rheumatoid arthritis
por: Snir, Omri, et al.
Publicado: (2014)

Health-related quality of life one year after the diagnosis of oesophageal cancer: a population-based study from the Swedish National Registry for Oesophageal and Gastric Cancer
por: Sunde, Berit, et al.
Publicado: (2021)

Health Avatar: An Informatics Platform for Personal and Private Big Data
por: Kim, Ju Han
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_h0hh2o23klgt3le82lh905c21s