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Angelica Sinensis Polysaccharides Stimulated UDP-Sugar Synthase Genes through Promoting Gene Expression of IGF-1 and IGF1R in Chondrocytes: Promoting Anti-Osteoarthritic Activity

BACKGROUND: Osteoarthritis (OA) is a chronic joints disease characterized by progressive degeneration of articular cartilage due to the loss of cartilage matrix. Previously, we found, for the first time, that an acidic glycan from Angelica Sinensis Polysaccharides (APSs), namely the APS-3c, could pr...

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Detalles Bibliográficos
Autores principales:	Wen, Yinxian, Li, Jing, Tan, Yang, Qin, Jun, Xie, Xianfei, Wang, Linlong, Mei, Qibing, Wang, Hui, Magdalou, Jacques, Chen, Liaobin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159308/ https://www.ncbi.nlm.nih.gov/pubmed/25202993 http://dx.doi.org/10.1371/journal.pone.0107024

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