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Mechanism of the pH-Induced Conformational Change in the Sensor Domain of the DraK Histidine Kinase via the E83, E105, and E107 Residues

The DraR/DraK two-component system was found to be involved in the differential regulation of antibiotic biosynthesis in a medium-dependent manner; however, its function and signaling and sensing mechanisms remain unclear. Here, we describe the solution structure of the extracellular sensor domain o...

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Detalles Bibliográficos
Autores principales: Yeo, Kwon Joo, Hong, Young-Soo, Jee, Jun-Goo, Lee, Jae Kyoung, Kim, Hyo Jeong, Park, Jin-Wan, Kim, Eun-Hee, Hwang, Eunha, Kim, Sang-Yoon, Lee, Eun-Gyeong, Kwon, Ohsuk, Cheong, Hae-Kap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159317/
https://www.ncbi.nlm.nih.gov/pubmed/25203403
http://dx.doi.org/10.1371/journal.pone.0107168