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Mechanism of the pH-Induced Conformational Change in the Sensor Domain of the DraK Histidine Kinase via the E83, E105, and E107 Residues
The DraR/DraK two-component system was found to be involved in the differential regulation of antibiotic biosynthesis in a medium-dependent manner; however, its function and signaling and sensing mechanisms remain unclear. Here, we describe the solution structure of the extracellular sensor domain o...
Autores principales: | Yeo, Kwon Joo, Hong, Young-Soo, Jee, Jun-Goo, Lee, Jae Kyoung, Kim, Hyo Jeong, Park, Jin-Wan, Kim, Eun-Hee, Hwang, Eunha, Kim, Sang-Yoon, Lee, Eun-Gyeong, Kwon, Ohsuk, Cheong, Hae-Kap |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159317/ https://www.ncbi.nlm.nih.gov/pubmed/25203403 http://dx.doi.org/10.1371/journal.pone.0107168 |
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