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NOX4 Mediates BMP4-Induced Upregulation of TRPC1 and 6 Protein Expressions in Distal Pulmonary Arterial Smooth Muscle Cells

RATIONALE: Our previous studies demonstrated that bone morphogenetic protein 4 (BMP4) mediated, elevated expression of canonical transient receptor potential (TRPC) largely accounts for the enhanced proliferation in pulmonary arterial smooth muscle cells (PASMCs). In the present study, we sought to...

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Detalles Bibliográficos
Autores principales: Jiang, Qian, Fu, Xin, Tian, Lichun, Chen, Yuqin, Yang, Kai, Chen, Xiuqing, Zhang, Jie, Lu, Wenju, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159322/
https://www.ncbi.nlm.nih.gov/pubmed/25203114
http://dx.doi.org/10.1371/journal.pone.0107135

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