Disruption of the ER-α36-EGFR/HER2 Positive Regulatory Loops Restores Tamoxifen Sensitivity in Tamoxifen Resistance Breast Cancer Cells

Tamoxifen provided a successful treatment for ER-positive breast cancer for many years. However, most breast tumors develop tamoxifen resistance and are eventually refractory to tamoxifen therapy. The molecular mechanisms underlying development of tamoxifen resistance have not been well established....

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Detalles Bibliográficos
Autores principales: Yin, Li, Zhang, Xin-Tian, Bian, Xiu-Wu, Guo, Yu-Ming, Wang, Zhao-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159333/
https://www.ncbi.nlm.nih.gov/pubmed/25203051
http://dx.doi.org/10.1371/journal.pone.0107369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159333/
https://www.ncbi.nlm.nih.gov/pubmed/25203051
http://dx.doi.org/10.1371/journal.pone.0107369

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