Structure of the N-Terminal Gyrase B Fragment in Complex with ADP⋅P(i) Reveals Rigid-Body Motion Induced by ATP Hydrolysis

Type II DNA topoisomerases are essential enzymes that catalyze topological rearrangement of double-stranded DNA using the free energy generated by ATP hydrolysis. Bacterial DNA gyrase is a prototype of this family and is composed of two subunits (GyrA, GyrB) that form a GyrA(2)GyrB(2) heterotetramer...

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Detalles Bibliográficos
Autores principales: Stanger, Frédéric V., Dehio, Christoph, Schirmer, Tilman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159350/
https://www.ncbi.nlm.nih.gov/pubmed/25202966
http://dx.doi.org/10.1371/journal.pone.0107289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159350/
https://www.ncbi.nlm.nih.gov/pubmed/25202966
http://dx.doi.org/10.1371/journal.pone.0107289

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