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Structure of the N-Terminal Gyrase B Fragment in Complex with ADP⋅P(i) Reveals Rigid-Body Motion Induced by ATP Hydrolysis
Type II DNA topoisomerases are essential enzymes that catalyze topological rearrangement of double-stranded DNA using the free energy generated by ATP hydrolysis. Bacterial DNA gyrase is a prototype of this family and is composed of two subunits (GyrA, GyrB) that form a GyrA(2)GyrB(2) heterotetramer...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159350/ https://www.ncbi.nlm.nih.gov/pubmed/25202966 http://dx.doi.org/10.1371/journal.pone.0107289 |