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DSas-6 and Ana2 Coassemble into Tubules to Promote Centriole Duplication and Engagement
Centrioles form cilia and centrosomes, organelles whose dysfunction is increasingly linked to human disease. Centriole duplication relies on a few conserved proteins (ZYG-1/Sak/Plk4, SAS-6, SAS-5/Ana2, and SAS-4), and is often initiated by the formation of an inner “cartwheel” structure. Here, we sh...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cell Press
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159445/ https://www.ncbi.nlm.nih.gov/pubmed/21145506 http://dx.doi.org/10.1016/j.devcel.2010.11.010 |