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An individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma
OBJECTIVE: To investigate the pathology and pathogenesis of and treatment methods for temporal bone verrucous carcinoma. MATERIALS AND METHODS: A single-patient report of verrucous carcinoma on the left external auditory canal is presented and analyzed along with all cases of temporal bone verrucous...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159496/ https://www.ncbi.nlm.nih.gov/pubmed/25214794 http://dx.doi.org/10.2147/OTT.S66145 |
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author | Tan, Haolei Liu, Yong Zhu, Gangcai Pi, Leiming Huang, Donghai Zhang, Xin |
author_facet | Tan, Haolei Liu, Yong Zhu, Gangcai Pi, Leiming Huang, Donghai Zhang, Xin |
author_sort | Tan, Haolei |
collection | PubMed |
description | OBJECTIVE: To investigate the pathology and pathogenesis of and treatment methods for temporal bone verrucous carcinoma. MATERIALS AND METHODS: A single-patient report of verrucous carcinoma on the left external auditory canal is presented and analyzed along with all cases of temporal bone verrucous carcinoma that have been documented in the English literature. RESULTS: Most of the patients with verrucous carcinoma of the temporal bone have histories of surgery, trauma, or infection, and verrucous carcinomas are sensitive to antimicrotubule chemotherapeutic medicines. Adjuvant radiation therapy is not effective, but surgical treatment might be relatively more effective. CONCLUSION: Temporal bone verrucous carcinoma has a poor prognosis; therefore, the preferred treatment is surgical resection facilitated with antimicrotubule chemotherapeutic treatment. Adjuvant radiation therapy is not a preferred treatment for temporal bone verrucous carcinoma. |
format | Online Article Text |
id | pubmed-4159496 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-41594962014-09-11 An individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma Tan, Haolei Liu, Yong Zhu, Gangcai Pi, Leiming Huang, Donghai Zhang, Xin Onco Targets Ther Original Research OBJECTIVE: To investigate the pathology and pathogenesis of and treatment methods for temporal bone verrucous carcinoma. MATERIALS AND METHODS: A single-patient report of verrucous carcinoma on the left external auditory canal is presented and analyzed along with all cases of temporal bone verrucous carcinoma that have been documented in the English literature. RESULTS: Most of the patients with verrucous carcinoma of the temporal bone have histories of surgery, trauma, or infection, and verrucous carcinomas are sensitive to antimicrotubule chemotherapeutic medicines. Adjuvant radiation therapy is not effective, but surgical treatment might be relatively more effective. CONCLUSION: Temporal bone verrucous carcinoma has a poor prognosis; therefore, the preferred treatment is surgical resection facilitated with antimicrotubule chemotherapeutic treatment. Adjuvant radiation therapy is not a preferred treatment for temporal bone verrucous carcinoma. Dove Medical Press 2014-09-04 /pmc/articles/PMC4159496/ /pubmed/25214794 http://dx.doi.org/10.2147/OTT.S66145 Text en © 2014 Tan et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Original Research Tan, Haolei Liu, Yong Zhu, Gangcai Pi, Leiming Huang, Donghai Zhang, Xin An individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma |
title | An individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma |
title_full | An individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma |
title_fullStr | An individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma |
title_full_unstemmed | An individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma |
title_short | An individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma |
title_sort | individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159496/ https://www.ncbi.nlm.nih.gov/pubmed/25214794 http://dx.doi.org/10.2147/OTT.S66145 |
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