Cargando…
Ultrasonographic findings relating to lymph node metastasis in single micropapillary thyroid cancer
BACKGROUND: In thyroid cancer, preoperative ultrasonography (US) is performed to detect the primary tumor and lymph node metastasis (LNM), which are related to prognosis. This study examined the relationships between specific US findings and LNM in micropapillary thyroid cancer (MPTC). METHODS: Data...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159533/ https://www.ncbi.nlm.nih.gov/pubmed/25169012 http://dx.doi.org/10.1186/1477-7819-12-273 |
_version_ | 1782334239843287040 |
---|---|
author | Lee, Yoon Se Lim, Yun-Sung Lee, Jin-Choon Wang, Soo-Geun Son, Seok-Man Kim, Sang-Soo Kim, In-Ju Lee, Byung-Joo |
author_facet | Lee, Yoon Se Lim, Yun-Sung Lee, Jin-Choon Wang, Soo-Geun Son, Seok-Man Kim, Sang-Soo Kim, In-Ju Lee, Byung-Joo |
author_sort | Lee, Yoon Se |
collection | PubMed |
description | BACKGROUND: In thyroid cancer, preoperative ultrasonography (US) is performed to detect the primary tumor and lymph node metastasis (LNM), which are related to prognosis. This study examined the relationships between specific US findings and LNM in micropapillary thyroid cancer (MPTC). METHODS: Data on 220 patients with solitary MPTC who underwent total thyroidectomy and neck dissection between 2008 and 2009 were evaluated retrospectively. We classified the US findings according to the nature, shape, echogenicity, extent, margin, and calcification of the primary tumor and evaluated the correlations between these findings and those of LNM. RESULTS: Hypoechogenicity (odds ratio = 2.331, P = 0.025) and marked hypoechogenicity (OR = 4.032, P = 0.016) of MPTC were risk factors for central LNM. All of the patients with lateral cervical LNM showed hypoechogenicity or marked hypoechogenicity. Hypoechogenicity (odds ratio = 5.349, P = 0.047) and other types of calcification (odds ratio = 2.495, P = 0.010) were significant risk factors for lateral cervical LNM. CONCLUSIONS: Specific sonographic findings (hypoechogenicity or marked hypoechogenicity, and calcification) suggest LNM. |
format | Online Article Text |
id | pubmed-4159533 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-41595332014-09-11 Ultrasonographic findings relating to lymph node metastasis in single micropapillary thyroid cancer Lee, Yoon Se Lim, Yun-Sung Lee, Jin-Choon Wang, Soo-Geun Son, Seok-Man Kim, Sang-Soo Kim, In-Ju Lee, Byung-Joo World J Surg Oncol Research BACKGROUND: In thyroid cancer, preoperative ultrasonography (US) is performed to detect the primary tumor and lymph node metastasis (LNM), which are related to prognosis. This study examined the relationships between specific US findings and LNM in micropapillary thyroid cancer (MPTC). METHODS: Data on 220 patients with solitary MPTC who underwent total thyroidectomy and neck dissection between 2008 and 2009 were evaluated retrospectively. We classified the US findings according to the nature, shape, echogenicity, extent, margin, and calcification of the primary tumor and evaluated the correlations between these findings and those of LNM. RESULTS: Hypoechogenicity (odds ratio = 2.331, P = 0.025) and marked hypoechogenicity (OR = 4.032, P = 0.016) of MPTC were risk factors for central LNM. All of the patients with lateral cervical LNM showed hypoechogenicity or marked hypoechogenicity. Hypoechogenicity (odds ratio = 5.349, P = 0.047) and other types of calcification (odds ratio = 2.495, P = 0.010) were significant risk factors for lateral cervical LNM. CONCLUSIONS: Specific sonographic findings (hypoechogenicity or marked hypoechogenicity, and calcification) suggest LNM. BioMed Central 2014-08-28 /pmc/articles/PMC4159533/ /pubmed/25169012 http://dx.doi.org/10.1186/1477-7819-12-273 Text en © Lee et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Lee, Yoon Se Lim, Yun-Sung Lee, Jin-Choon Wang, Soo-Geun Son, Seok-Man Kim, Sang-Soo Kim, In-Ju Lee, Byung-Joo Ultrasonographic findings relating to lymph node metastasis in single micropapillary thyroid cancer |
title | Ultrasonographic findings relating to lymph node metastasis in single micropapillary thyroid cancer |
title_full | Ultrasonographic findings relating to lymph node metastasis in single micropapillary thyroid cancer |
title_fullStr | Ultrasonographic findings relating to lymph node metastasis in single micropapillary thyroid cancer |
title_full_unstemmed | Ultrasonographic findings relating to lymph node metastasis in single micropapillary thyroid cancer |
title_short | Ultrasonographic findings relating to lymph node metastasis in single micropapillary thyroid cancer |
title_sort | ultrasonographic findings relating to lymph node metastasis in single micropapillary thyroid cancer |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159533/ https://www.ncbi.nlm.nih.gov/pubmed/25169012 http://dx.doi.org/10.1186/1477-7819-12-273 |
work_keys_str_mv | AT leeyoonse ultrasonographicfindingsrelatingtolymphnodemetastasisinsinglemicropapillarythyroidcancer AT limyunsung ultrasonographicfindingsrelatingtolymphnodemetastasisinsinglemicropapillarythyroidcancer AT leejinchoon ultrasonographicfindingsrelatingtolymphnodemetastasisinsinglemicropapillarythyroidcancer AT wangsoogeun ultrasonographicfindingsrelatingtolymphnodemetastasisinsinglemicropapillarythyroidcancer AT sonseokman ultrasonographicfindingsrelatingtolymphnodemetastasisinsinglemicropapillarythyroidcancer AT kimsangsoo ultrasonographicfindingsrelatingtolymphnodemetastasisinsinglemicropapillarythyroidcancer AT kiminju ultrasonographicfindingsrelatingtolymphnodemetastasisinsinglemicropapillarythyroidcancer AT leebyungjoo ultrasonographicfindingsrelatingtolymphnodemetastasisinsinglemicropapillarythyroidcancer |