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Biofragments: An Approach towards Predicting Protein Function Using Biologically Related Fragments and its Application to Mycobacterium tuberculosis CYP126

We present a novel fragment-based approach that tackles some of the challenges for chemical biology of predicting protein function. The general approach, which we have termed biofragments, comprises two key stages. First, a biologically relevant fragment library (biofragment library) can be designed...

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Detalles Bibliográficos
Autores principales:	Hudson, Sean A, Mashalidis, Ellene H, Bender, Andreas, McLean, Kirsty J, Munro, Andrew W, Abell, Chris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2014
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159592/ https://www.ncbi.nlm.nih.gov/pubmed/24677424 http://dx.doi.org/10.1002/cbic.201300697

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