Neuroendocrine and sympathetic responses to an orexin receptor antagonist, SB-649868, and Alprazolam following insulin-induced hypoglycemia in humans

RATIONALE: The orexin-hypocretin system is important for translating peripheral metabolic signals and central neuronal inputs to a diverse range of behaviors, from feeding, motivation and arousal, to sleep and wakefulness. Orexin signaling is thus an exciting potential therapeutic target for disorde...

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Detalles Bibliográficos
Autores principales: Patel, Ameera X., Miller, Sam R., Nathan, Pradeep J., Kanakaraj, Ponmani, Napolitano, Antonella, Lawrence, Philip, Koch, Annelize, Bullmore, Edward T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159598/
https://www.ncbi.nlm.nih.gov/pubmed/24770625
http://dx.doi.org/10.1007/s00213-014-3520-7

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