Disruption of Phosphoinositide-Specific Phospholipases Cγ1 Contributes to Extracellular Matrix Synthesis of Human Osteoarthritis Chondrocytes

Osteoarthritis (OA) is a degenerative joint disease characterized by articular cartilage degradation including extracellular matrix (ECM) degradation and cell loss. It is known that phosphoinositide-specific phospholipase γ1 (PLCγ1) can trigger several signaling pathways to regulate cell metabolism....

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Detalles Bibliográficos
Autores principales: Zeng, Guoqing, Cui, Xu, Liu, Zejun, Zhao, Honghai, Zheng, Xinpeng, Zhang, Bing, Xia, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159791/
https://www.ncbi.nlm.nih.gov/pubmed/25073093
http://dx.doi.org/10.3390/ijms150813236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159791/
https://www.ncbi.nlm.nih.gov/pubmed/25073093
http://dx.doi.org/10.3390/ijms150813236

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