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Disruption of Phosphoinositide-Specific Phospholipases Cγ1 Contributes to Extracellular Matrix Synthesis of Human Osteoarthritis Chondrocytes

Osteoarthritis (OA) is a degenerative joint disease characterized by articular cartilage degradation including extracellular matrix (ECM) degradation and cell loss. It is known that phosphoinositide-specific phospholipase γ1 (PLCγ1) can trigger several signaling pathways to regulate cell metabolism....

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Detalles Bibliográficos
Autores principales:	Zeng, Guoqing, Cui, Xu, Liu, Zejun, Zhao, Honghai, Zheng, Xinpeng, Zhang, Bing, Xia, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159791/ https://www.ncbi.nlm.nih.gov/pubmed/25073093 http://dx.doi.org/10.3390/ijms150813236

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