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Non-Synonymous Single Nucleotide Polymorphisms in the P2X Receptor Genes: Association with Diseases, Impact on Receptor Functions and Potential Use as Diagnosis Biomarkers

P2X receptors are Ca(2+)-permeable cationic channels in the cell membranes, where they play an important role in mediating a diversity of physiological and pathophysiological functions of extracellular ATP. Mammalian cells express seven P2X receptor genes. Single nucleotide polymorphisms (SNPs) are...

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Detalles Bibliográficos
Autores principales:	Caseley, Emily A., Muench, Stephen P., Roger, Sebastien, Mao, Hong-Ju, Baldwin, Stephen A., Jiang, Lin-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159798/ https://www.ncbi.nlm.nih.gov/pubmed/25079442 http://dx.doi.org/10.3390/ijms150813344

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