Cargando…

The Constituents of Roots and Stems of Illigera luzonensis and Their Anti-Platelet Aggregation Effects

Phytochemical investigation of the roots and stems of Illigera luzonensis afforded two new aporphine alkaloids (1) and (2), one new bisdehydroaporphine alkaloid (3), and one new benzenoid (4), along with 28 known structures. The structures of new compounds were elucidated by spectral and MS analysis...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Chieh-Hung, Chan, Yu-Yi, Kuo, Ping-Chung, Chen, Yu-Fon, Chang, Ren-Jie, Chen, Ih-Sheng, Wu, Shwu-Jen, Wu, Tian-Shung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159803/
https://www.ncbi.nlm.nih.gov/pubmed/25089876
http://dx.doi.org/10.3390/ijms150813424
_version_ 1782334282183737344
author Huang, Chieh-Hung
Chan, Yu-Yi
Kuo, Ping-Chung
Chen, Yu-Fon
Chang, Ren-Jie
Chen, Ih-Sheng
Wu, Shwu-Jen
Wu, Tian-Shung
author_facet Huang, Chieh-Hung
Chan, Yu-Yi
Kuo, Ping-Chung
Chen, Yu-Fon
Chang, Ren-Jie
Chen, Ih-Sheng
Wu, Shwu-Jen
Wu, Tian-Shung
author_sort Huang, Chieh-Hung
collection PubMed
description Phytochemical investigation of the roots and stems of Illigera luzonensis afforded two new aporphine alkaloids (1) and (2), one new bisdehydroaporphine alkaloid (3), and one new benzenoid (4), along with 28 known structures. The structures of new compounds were elucidated by spectral and MS analysis. Among the isolated compounds, (1) and (4–13) were subjected into the examination for their inhibitory effects on the aggregation of washed rabbit platelets.
format Online
Article
Text
id pubmed-4159803
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-41598032014-09-18 The Constituents of Roots and Stems of Illigera luzonensis and Their Anti-Platelet Aggregation Effects Huang, Chieh-Hung Chan, Yu-Yi Kuo, Ping-Chung Chen, Yu-Fon Chang, Ren-Jie Chen, Ih-Sheng Wu, Shwu-Jen Wu, Tian-Shung Int J Mol Sci Article Phytochemical investigation of the roots and stems of Illigera luzonensis afforded two new aporphine alkaloids (1) and (2), one new bisdehydroaporphine alkaloid (3), and one new benzenoid (4), along with 28 known structures. The structures of new compounds were elucidated by spectral and MS analysis. Among the isolated compounds, (1) and (4–13) were subjected into the examination for their inhibitory effects on the aggregation of washed rabbit platelets. MDPI 2014-07-31 /pmc/articles/PMC4159803/ /pubmed/25089876 http://dx.doi.org/10.3390/ijms150813424 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Huang, Chieh-Hung
Chan, Yu-Yi
Kuo, Ping-Chung
Chen, Yu-Fon
Chang, Ren-Jie
Chen, Ih-Sheng
Wu, Shwu-Jen
Wu, Tian-Shung
The Constituents of Roots and Stems of Illigera luzonensis and Their Anti-Platelet Aggregation Effects
title The Constituents of Roots and Stems of Illigera luzonensis and Their Anti-Platelet Aggregation Effects
title_full The Constituents of Roots and Stems of Illigera luzonensis and Their Anti-Platelet Aggregation Effects
title_fullStr The Constituents of Roots and Stems of Illigera luzonensis and Their Anti-Platelet Aggregation Effects
title_full_unstemmed The Constituents of Roots and Stems of Illigera luzonensis and Their Anti-Platelet Aggregation Effects
title_short The Constituents of Roots and Stems of Illigera luzonensis and Their Anti-Platelet Aggregation Effects
title_sort constituents of roots and stems of illigera luzonensis and their anti-platelet aggregation effects
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159803/
https://www.ncbi.nlm.nih.gov/pubmed/25089876
http://dx.doi.org/10.3390/ijms150813424
work_keys_str_mv AT huangchiehhung theconstituentsofrootsandstemsofilligeraluzonensisandtheirantiplateletaggregationeffects
AT chanyuyi theconstituentsofrootsandstemsofilligeraluzonensisandtheirantiplateletaggregationeffects
AT kuopingchung theconstituentsofrootsandstemsofilligeraluzonensisandtheirantiplateletaggregationeffects
AT chenyufon theconstituentsofrootsandstemsofilligeraluzonensisandtheirantiplateletaggregationeffects
AT changrenjie theconstituentsofrootsandstemsofilligeraluzonensisandtheirantiplateletaggregationeffects
AT chenihsheng theconstituentsofrootsandstemsofilligeraluzonensisandtheirantiplateletaggregationeffects
AT wushwujen theconstituentsofrootsandstemsofilligeraluzonensisandtheirantiplateletaggregationeffects
AT wutianshung theconstituentsofrootsandstemsofilligeraluzonensisandtheirantiplateletaggregationeffects
AT huangchiehhung constituentsofrootsandstemsofilligeraluzonensisandtheirantiplateletaggregationeffects
AT chanyuyi constituentsofrootsandstemsofilligeraluzonensisandtheirantiplateletaggregationeffects
AT kuopingchung constituentsofrootsandstemsofilligeraluzonensisandtheirantiplateletaggregationeffects
AT chenyufon constituentsofrootsandstemsofilligeraluzonensisandtheirantiplateletaggregationeffects
AT changrenjie constituentsofrootsandstemsofilligeraluzonensisandtheirantiplateletaggregationeffects
AT chenihsheng constituentsofrootsandstemsofilligeraluzonensisandtheirantiplateletaggregationeffects
AT wushwujen constituentsofrootsandstemsofilligeraluzonensisandtheirantiplateletaggregationeffects
AT wutianshung constituentsofrootsandstemsofilligeraluzonensisandtheirantiplateletaggregationeffects