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Simvastatin Attenuates the Oxidative Stress, Endothelial Thrombogenicity and the Inducibility of Atrial Fibrillation in a Rat Model of Ischemic Heart Failure

Increased atrial oxidative stress has an important role in inducing and maintaining atrial fibrillation (AF), and the activation of the small GTPase Rac1 contributes to the oxidative stress. We investigated the relationship of Rac1, atrial endothelial thromboprotective markers and AF inducibility an...

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Detalles Bibliográficos
Autores principales: Cho, Kyoung-Im, Koo, Sang-Ho, Cha, Tae-Joon, Heo, Jung-Ho, Kim, Hyun-Su, Jo, Gee-Bum, Lee, Jae-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159883/
https://www.ncbi.nlm.nih.gov/pubmed/25153633
http://dx.doi.org/10.3390/ijms150814803