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Methyl protodioscin induces G2/M cell cycle arrest and apoptosis in A549 human lung cancer cells
BACKGROUND: Methyl protodioscin (MPD) is a furostanol bisglycoside with antitumor properties. It has been shown to reduce proliferation, cause cell cycle arrest. OBJECTIVE: The present study elucidates the mechanism underlying MPD's apoptotic effects, using the A549 human lung cancer cell line....
Autores principales: | Bai, Yang, Qu, Xiao-Yuan, Yin, Jun-Qiang, Wu, Liangcai, Jiang, Hong, Long, Han-Wu, Jia, Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159926/ https://www.ncbi.nlm.nih.gov/pubmed/25210320 http://dx.doi.org/10.4103/0973-1296.137373 |
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