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Trans-cranial opening of the blood-brain barrier in targeted regions using a stereotaxic brain atlas and focused ultrasound energy

OBJECTIVE: The blood-brain barrier (BBB) protects the brain by preventing the entry of large molecules; this poses a major obstacle for the delivery of drugs to the brain. A novel technique using focused ultrasound (FUS) energy combined with microbubble contrast agents has been widely used for non-i...

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Detalles Bibliográficos
Autores principales:	Bing, Chenchen, Ladouceur-Wodzak, Michelle, Wanner, Clinton R, Shelton, John M, Richardson, James A, Chopra, Rajiv
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160001/ https://www.ncbi.nlm.nih.gov/pubmed/25232482 http://dx.doi.org/10.1186/2050-5736-2-13

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