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MID1 Catalyzes the Ubiquitination of Protein Phosphatase 2A and Mutations within Its Bbox1 Domain Disrupt Polyubiquitination of Alpha4 but Not of PP2Ac

MID1 is a microtubule-associated protein that belongs to the TRIM family. MID1 functions as an ubiquitin E3 ligase, and recently was shown to catalyze the polyubiquitination of, alpha4, a protein regulator of protein phosphatase 2A (PP2A). It has been hypothesized that MID1 regulates PP2A, requiring...

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Detalles Bibliográficos
Autores principales:	Du, Haijuan, Wu, Kuanlin, Didoronkute, Alma, Levy, Marcus V. A., Todi, Nimish, Shchelokova, Anna, Massiah, Michael A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160256/ https://www.ncbi.nlm.nih.gov/pubmed/25207814 http://dx.doi.org/10.1371/journal.pone.0107428

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