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Light-Induced N(2)O Production from a Non-heme Iron–Nitrosyl Dimer

[Image: see text] Two non-heme iron–nitrosyl species, [Fe(2)(N-Et-HPTB)(O(2)CPh)(NO)(2)](BF(4))(2) (1a) and [Fe(2)(N-Et-HPTB)(DMF)(2)(NO)(OH)](BF(4))(3) (2a), are characterized by FTIR and resonance Raman spectroscopy. Binding of NO is reversible in both complexes, which are prone to NO photolysis u...

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Autores principales: Jiang, Yunbo, Hayashi, Takahiro, Matsumura, Hirotoshi, Do, Loi H., Majumdar, Amit, Lippard, Stephen J., Moënne-Loccoz, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160282/
https://www.ncbi.nlm.nih.gov/pubmed/25158917
http://dx.doi.org/10.1021/ja504343t
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author Jiang, Yunbo
Hayashi, Takahiro
Matsumura, Hirotoshi
Do, Loi H.
Majumdar, Amit
Lippard, Stephen J.
Moënne-Loccoz, Pierre
author_facet Jiang, Yunbo
Hayashi, Takahiro
Matsumura, Hirotoshi
Do, Loi H.
Majumdar, Amit
Lippard, Stephen J.
Moënne-Loccoz, Pierre
author_sort Jiang, Yunbo
collection PubMed
description [Image: see text] Two non-heme iron–nitrosyl species, [Fe(2)(N-Et-HPTB)(O(2)CPh)(NO)(2)](BF(4))(2) (1a) and [Fe(2)(N-Et-HPTB)(DMF)(2)(NO)(OH)](BF(4))(3) (2a), are characterized by FTIR and resonance Raman spectroscopy. Binding of NO is reversible in both complexes, which are prone to NO photolysis under visible light illumination. Photoproduction of N(2)O occurs in high yield for 1a but not 2a. Low-temperature FTIR photolysis experiments with 1a in acetonitrile do not reveal any intermediate species, but in THF at room temperature, a new {FeNO}(7) species quickly forms under illumination and exhibits a ν(NO) vibration indicative of nitroxyl-like character. This metastable species reacts further under illumination to produce N(2)O. A reaction mechanism is proposed, and implications for NO reduction in flavodiiron proteins are discussed.
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spelling pubmed-41602822015-08-12 Light-Induced N(2)O Production from a Non-heme Iron–Nitrosyl Dimer Jiang, Yunbo Hayashi, Takahiro Matsumura, Hirotoshi Do, Loi H. Majumdar, Amit Lippard, Stephen J. Moënne-Loccoz, Pierre J Am Chem Soc [Image: see text] Two non-heme iron–nitrosyl species, [Fe(2)(N-Et-HPTB)(O(2)CPh)(NO)(2)](BF(4))(2) (1a) and [Fe(2)(N-Et-HPTB)(DMF)(2)(NO)(OH)](BF(4))(3) (2a), are characterized by FTIR and resonance Raman spectroscopy. Binding of NO is reversible in both complexes, which are prone to NO photolysis under visible light illumination. Photoproduction of N(2)O occurs in high yield for 1a but not 2a. Low-temperature FTIR photolysis experiments with 1a in acetonitrile do not reveal any intermediate species, but in THF at room temperature, a new {FeNO}(7) species quickly forms under illumination and exhibits a ν(NO) vibration indicative of nitroxyl-like character. This metastable species reacts further under illumination to produce N(2)O. A reaction mechanism is proposed, and implications for NO reduction in flavodiiron proteins are discussed. American Chemical Society 2014-08-12 2014-09-10 /pmc/articles/PMC4160282/ /pubmed/25158917 http://dx.doi.org/10.1021/ja504343t Text en Copyright © 2014 American Chemical Society Terms of Use (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html)
spellingShingle Jiang, Yunbo
Hayashi, Takahiro
Matsumura, Hirotoshi
Do, Loi H.
Majumdar, Amit
Lippard, Stephen J.
Moënne-Loccoz, Pierre
Light-Induced N(2)O Production from a Non-heme Iron–Nitrosyl Dimer
title Light-Induced N(2)O Production from a Non-heme Iron–Nitrosyl Dimer
title_full Light-Induced N(2)O Production from a Non-heme Iron–Nitrosyl Dimer
title_fullStr Light-Induced N(2)O Production from a Non-heme Iron–Nitrosyl Dimer
title_full_unstemmed Light-Induced N(2)O Production from a Non-heme Iron–Nitrosyl Dimer
title_short Light-Induced N(2)O Production from a Non-heme Iron–Nitrosyl Dimer
title_sort light-induced n(2)o production from a non-heme iron–nitrosyl dimer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160282/
https://www.ncbi.nlm.nih.gov/pubmed/25158917
http://dx.doi.org/10.1021/ja504343t
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