Cargando…

A historical perspective on the lateral diffusion model of GTPase activation and related coupling of membrane signaling proteins

Aspects of our discovery of lateral diffusion of the G protein coupled receptor (GPCR) rhodopsin and that a single activated rhodopsin can non-covalently catalyze GTP binding to thousands of GTPases per second on rod disk membranes via this diffusion are summarized herein. Rapid GTPase coupling to m...

Descripción completa

Detalles Bibliográficos
Autor principal: Liebman, Paul A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160331/
https://www.ncbi.nlm.nih.gov/pubmed/25279248
http://dx.doi.org/10.4161/cl.29389