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A historical perspective on the lateral diffusion model of GTPase activation and related coupling of membrane signaling proteins
Aspects of our discovery of lateral diffusion of the G protein coupled receptor (GPCR) rhodopsin and that a single activated rhodopsin can non-covalently catalyze GTP binding to thousands of GTPases per second on rod disk membranes via this diffusion are summarized herein. Rapid GTPase coupling to m...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Landes Bioscience
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160331/ https://www.ncbi.nlm.nih.gov/pubmed/25279248 http://dx.doi.org/10.4161/cl.29389 |