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A historical perspective on the lateral diffusion model of GTPase activation and related coupling of membrane signaling proteins

Aspects of our discovery of lateral diffusion of the G protein coupled receptor (GPCR) rhodopsin and that a single activated rhodopsin can non-covalently catalyze GTP binding to thousands of GTPases per second on rod disk membranes via this diffusion are summarized herein. Rapid GTPase coupling to m...

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Detalles Bibliográficos
Autor principal:	Liebman, Paul A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2014
Materias:	Reasoned Debate
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160331/ https://www.ncbi.nlm.nih.gov/pubmed/25279248 http://dx.doi.org/10.4161/cl.29389

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