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Differential Apicobasal VEGF Signaling at Vascular Blood-Neural Barriers
The vascular endothelium operates in a highly polarized environment, but to date there has been little exploration of apicobasal polarization of its signaling. We show that VEGF-A, histamine, IGFBP3, and LPA trigger unequal endothelial responses when acting from the circulation or the parenchymal si...
Autores principales: | Hudson, Natalie, Powner, Michael B., Sarker, Mosharraf H., Burgoyne, Thomas, Campbell, Matthew, Ockrim, Zoe K., Martinelli, Roberta, Futter, Clare E., Grant, Maria B., Fraser, Paul A., Shima, David T., Greenwood, John, Turowski, Patric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160345/ https://www.ncbi.nlm.nih.gov/pubmed/25175707 http://dx.doi.org/10.1016/j.devcel.2014.06.027 |
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