MAPK-activated protein kinase 2-deficiency causes hyperacute tumor necrosis factor-induced inflammatory shock

BACKGROUND: MAPK-activated protein kinase 2 (MK2) plays a pivotal role in the cell response to (inflammatory) stress. Among others, MK2 is known to be involved in the regulation of cytokine mRNA metabolism and regulation of actin cytoskeleton dynamics. Previously, MK2-deficient mice were shown to be...

Descripción completa

Detalles Bibliográficos
Autores principales: Vandendriessche, Benjamin, Goethals, An, Simats, Alba, Van Hamme, Evelien, Brouckaert, Peter, Cauwels, Anje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160542/
https://www.ncbi.nlm.nih.gov/pubmed/25185746
http://dx.doi.org/10.1186/s12899-014-0005-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160542/
https://www.ncbi.nlm.nih.gov/pubmed/25185746
http://dx.doi.org/10.1186/s12899-014-0005-1

Ejemplares similares