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Hirano body expression impairs spatial working memory in a novel mouse model

INTRODUCTION: Hirano bodies are actin-rich intracellular inclusions found in the brains of patients with neurodegenerative conditions such as Alzheimer's disease or frontotemporal lobar degeneration-tau. While Hirano body ultrastructure and protein composition have been well studied, little is...

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Detalles Bibliográficos
Autores principales: Furgerson, Matthew, Clark, Jason K., Crystal, Jonathon D., Wagner, John J., Fechheimer, Marcus, Furukawa, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160558/
https://www.ncbi.nlm.nih.gov/pubmed/25178488
http://dx.doi.org/10.1186/s40478-014-0131-9